ABSTRACT
A double-blind placebo-controlled trial was undertaken to evaluate the synergic effects of coenzymeQ10 (CoQ10) and creatine (Cr) through oral supplementation on the intermittent short duration high-intensity exercise on a cycle ergometer. Twenty-eight male athletes were divided into four groups of CoQ10 and Cr (CoQ10+Cr), CoQ10 (CoQ10+Pl), Cr (Pl+Cr) and placebo group (Pl+Pl). Each participant was instructed to have 100 mg of CoQ10 and/or 5 g of Cr per day for 2 weeks. Repetitive 5 bouts of 10-sec high-intensity cycle exercise tests were performed before and after supplementations. After supplementations, subjects in (CoQ10+Cr) revealed most improved performance in mean power outputs at the 2<sup>nd</sup> (p<0.05), the 3<sup>rd</sup> (p<0.05), the 4<sup>th</sup> (p<0.05) and the 5<sup>th</sup> set (p=0.06), comparing with the participants in the other 3 groups. These findings suggest that enhanced mean power output on repetitive short duration high-intensity exercise can be acquired after supplementing CoQ10 combined with Cr.